Nano robotics

it has been observed that only well-motivated, highly
compliant patients are suitable for photoradiation (2). A possible
explanation is that this could depend not only on the exhausting
photo(chemio) therapeutic algorithms, but also on the fact that
systemic irradiation, even when successful, always provokes
transient darkening of the non-affected skin, with a negative
psychological impact related to the increased chromatic difference
with the vitiligo patches. Instead, as repigmentation obtained with
the focused UV-B microphototherapy is limited to the treated
vitiligo areas and the radiation is performed only once or twice per
month, the novel phototherapy treatment is extremely well accepted
by the vitiligo patients.

Follow-up studies are needed to ascertain whether the repigmentation
induced by this limited irradiation method is permanent.

Figure 1 Repigmentation after microphototherapy on actively treated
subjects and controls.

*References*

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